Symptoms & Signs of Autoimmune Disease

This is an evolving list of common autoimmune disease symptoms as well as signs of disease. Many of these complex symptoms and signs overlap and are experienced within various conditions. Our understanding is constantly shifting as more information comes to light.

 

Digestive

Abdominal pain

Acid reflux

Bloating

Blood or mucus in stool

Constipation

Diarrhea

Food intolerance (e.g. lactose)

Food sensitivities

Inability to gain weight

Loss of appetite

Malabsorption

Nausea

Pale, pungent stool

Swollen belly (infancy, early childhood)

Vomiting

 

Joints, Muscles, & Bones

Bone growth slowing or stopping (e.g. jaw, short stature)

Bone pain

Impaired coordination

Inflammation

Joint pain, stiffness, swelling

Muscle aches, pains

Muscle weakness

Osteomalacia (softening of bones)

 

Neurological

Anxiety

Balance difficulties

Blurry vision

Brain fog / cognitive difficulties (lack of mental clarity, difficulty concentrating)

Compulsions, phobias, hyper focus (on food, germs, personal safety, etc.)

Depression

Disordered eating

Dizziness

Headaches

Insomnia

Learning disability

Lightheadedness

Memory loss

Migraines

Numbness and tingling

Rapid or irregular heartbeat

Tremors

Seizures

Vision changes

 

Psychosocial

Body dysmorphia

Irritability

Social anxiety

Self-harm

Suicidal ideation

 

Reproductive/Urinary

Absent menstruation (amenorrhea)

Bladder pain

Delayed onset of puberty

Frequent urination

Infertility

Irregular menstruation

Miscarriage

Sexual difficulties

Urinary difficulties

 

Skin

Dry eyes

Dry mouth

Dry skin

Hair loss

Inflammation

Itching

Rash

 

Other

Anemia

Chest pain

Emotional volatility

Failure to thrive (FTT)

Fatigue

Fever

Inability to form tooth enamel

Mouth ulcers

Pain

Shortness of breath

Swollen glands

Temperature sensitivity

Thin or thinning hair

Weight gain or loss