Ocular cicatricial pemphigoid

Overview

A form of mucous membrane pemphigoid that causes scarring of the conjunctiva (the inside lining) of the eyes. If left untreated, it can lead to vision loss and permanent eyelid and corneal damage.

Common Symptoms

Eye redness and irritation, tearing, mucus discharge, sensitivity to light, ulcers in the eyes, mouth, genitals, and anus, hoarseness and difficulty swallowing.

Coexisting Diseases and Conditions

Dry eye syndrome and alopecia areata.

Risk Factors and Prevalence

Being female, 60 years and older, and using certain medications have been associated with the development of OCP.

Sources

  1. Article Sources

    1. Butt, Z., Kaufman, D., McNab, A., & McKelvie, P. (1998). Drug-induced ocular cicatricial pemphigoid: A series of clinico-pathological reports. Eye, 12(2), 285–290. https://doi.org/10.1038/eye.1998.66.

    2. Ocular cicatricial pemphigoid | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program. (n.d.). Https://Rarediseases.Info.Nih.Gov/Diseases/8759/Ocular-Cicatricial-Pemphigoid. Retrieved July 9, 2021, from https://rarediseases.info.nih.gov/diseases/8759/ocular-cicatricial-pemphigoid. 

    3. Ocular Cicatricial Pemphigoid | Johns Hopkins Wilmer Eye Institute. (n.d.). Retrieved July 9, 2021, from https://www.hopkinsmedicine.org/wilmer/conditions/pemphigoid.html.

    4. Schonberg, S., & Stokkermans, T. J. (2021). Ocular Pemphigoid. In StatPearls. StatPearls Publishing. http://www.ncbi.nlm.nih.gov/books/NBK526100/.