Bullous pemphigoid

 

Overview

A skin disease characterized by large fluid-filled blisters on the areas that flex, such as the lower abdomen, upper thighs, or armpits, due to autoantibodies targeting the skin.

Common Symptoms

Itchy skin (pre-blister formation), large, tough blisters along creases/folds in the skin, reddish/darker skin around blisters, eczema, rashes, and small mouth sores.

Coexisting Diseases and Conditions

Psoriasis, lichen planus, diabetes, rheumatoid arthritis, ulcerative colitis, and multiple sclerosis.

Risk Factors and Prevalence

Risk increases with age as it typically only affects older individuals. Males tend to be more commonly affected than females. There are known genetic predispositions to the disease. Patients with neurological diseases, including strokes, dementia, Parkinson’s disease, and psoriasis are at increased risk. Certain medications, injuries, or skin infections can also be triggers.

Sources

  1. Article Sources

    1. aocd.org. (n.d.). Https://Www.Aocd.Org/Page/BullousPemphigoid. Retrieved July 12, 2021, from https://www.aocd.org/page/BullousPemphigoid

    2. Bullous pemphigoid | DermNet NZ. (n.d.). Https://Dermnetnz.Org/Topics/Bullous-Pemphigoid/. Retrieved July 12, 2021, from https://dermnetnz.org/topics/bullous-pemphigoid/

    3. Bullous pemphigoid. (2018, April 17). Nhs.Uk. https://www.nhs.uk/conditions/bullous-pemphigoid/

    4. Bullous pemphigoid—Symptoms and causes. (n.d.). Mayo Clinic. Retrieved July 12, 2021, from https://www.mayoclinic.org/diseases-conditions/bullous-pemphigoid/symptoms-causes/syc-20350414