Myalgic encephalomyelitis (ME), also known as Chronic fatigue syndrome (CFS), is characterized by overwhelming tiredness that is not improved by rest. Those with the condition suffer from fatigue that is so severe it inhibits them from performing daily activities. Cognitive and sleep issues are also common in ME/CFS patients. Due to its similar appearance to other illnesses, diagnosis is challenging. ME/CFS is chronic and sometimes unpredictable, with symptoms and severity fluctuating over time.
Presently, the causes of ME/CFS are unknown. There are no laboratory tests specifically designed to diagnose the condition, nor are there cures available. Symptom management is the current care strategy for most patients.