Also known as immunoglobulin G4-related disease, AIP is caused by an immune system attack on the pancreas which causes chronic inflammation, enlargement, or a mass in the pancreas. The subtypes of AIP are known as type 1 and type 2, and affect different parts of the body. Type 1 affects multiple organs; the pancreas, liver bile ducts, salivary glands, kidneys, and lymph nodes, while Type 2 only affects the pancreas.
Dark urine, pale and/or floating stool, nausea and vomiting, loss of appetite, unexplained weight loss, painless jaundice, upper abdomen and/ or middle back pain, weakness, and extreme fatigue.
Jaundice, ulcerative colitis, diabetes, pancreatic and bile duct stricture, pancreatic calcifications or stones, and pancreatic exocrine insufficiency.
AIP Type 1:
Males aged 60 -70.
AIP Type 2:
Younger age; usually over 40, affecting males and females at equal rates. The frequency of both types varies according to geographical location.
Autoimmune Pancreatitis: Symptoms, Treatments & Tests. (n.d.). Cleveland Clinic. Retrieved July 12, 2021, from https://my.clevelandclinic.org/health/diseases/17936-autoimmune-pancreatitis
Autoimmune pancreatitis—Symptoms and causes. (n.d.). Mayo Clinic. Retrieved July 12, 2021, from https://www.mayoclinic.org/diseases-conditions/autoimmune-pancreatitis/symptoms-causes/syc-20369800
Fan, B.-G., & Andrén-Sandberg, Å. (2009). Autoimmune pancreatitis. North American Journal of Medical Sciences, 1(4), 148–151. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364658/
