Back Understanding Autoimmune Disease
Understanding Autoimmune Disease
Back Resources for Hope and Health
Resources for Hope and Health
Back Autoimmune Research & News
Autoimmune Research & News
Back Who We Are & How We Help
Who We Are & How We Help
an icon of a microscope, indicating research and science
Research Grants
& Projects
Search
Dec 15, 2025 Promising Phase III Trial for Immune Thrombocytopenia Treatment
Immune thrombocytopenia (ITP) is an autoimmune disease where the immune system attacks platelets in the blood, resulting in a low platelet count. Because platelets normally help the blood clot, low platelet counts can lead to significant bruising or bleeding. Patients with ITP can be treated with steroids, but those that don’t respond to this require […]
  • Autoimmune Diseases
  • Clinical Trials
  • Therapies
Read Post
Dec 12, 2025 What We Know Now About Inverse Vaccines
Since inverse vaccines were first proposed as a potential means of retraining the immune system in autoimmune disease, new research has clarified how immune tolerance is actively enforced at the cellular level and why certain delivery strategies may be more effective than others. A recent study published in Nature sheds light on the role of a specialized […]
  • Research Studies
  • Therapies
Read Post
Dec 10, 2025 Rising Investment in Autoimmune Disease Diagnosis
A new global market analysis projects rapid growth in autoimmune disease diagnostic testing over the next several years, driven by rising rates of autoimmune conditions and increased emphasis on earlier detection. While market reports typically focus on industry trends, this growth may have meaningful implications for people living with autoimmune disease. Systemic autoimmune diseases, such […]
  • Autoimmune Diseases
  • Diagnostic Testing
  • IBD (Crohn’s and UC)
  • Lupus
  • Multiple Sclerosis
  • Rheumatoid Arthritis
Read Post
Dec 02, 2025 How Oral Lichen Planus Connects to Systemic Autoimmune Disease
A literature review recently published in the Journal of Dental Research examined current evidence on the relationship between systemic diseases and oral lichen planus (OLP), an autoimmune disorder in which CD8+ T cells target basal keratinocytes in the oral mucosa. OLP affects about 1% of the population and may also involve other mucosal sites, including the esophagus […]
  • Autoimmune Diseases
  • Celiac Disease
  • Research Studies
  • Risk Factors
  • Thyroid Disease
  • Type 1 Diabetes
Read Post
Nov 28, 2025 Brain Waste-Clearance Impairments Tied to ME/CFS
A new perspective article from Stanford researchers proposes that dysfunction of the glymphatic system, the brain’s waste-clearance network, may be a central contributor to the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The glymphatic system typically removes metabolic byproducts such as lactate, glutamate, tau, and beta-amyloid, especially during deep sleep. When this system is […]
  • ME/CFS
  • Research Studies
Read Post
Nov 27, 2025 Could AI Help Personalize Stem Cell Therapy for Lupus?
Researchers are exploring how artificial intelligence could help improve mesenchymal stem cell (MSC) therapies for systemic lupus erythematosus by making treatments more consistent and personalized. MSC therapy has shown promise in lupus because these cells can help calm immune overactivity while also supporting tissue repair. However, results across studies have been mixed. Differences in cell […]
  • Lupus
  • Research Studies
  • Therapies
Read Post
Nov 26, 2025 c-Maf: The Immune “Brake” Shaping Autoimmune Disease
The transcription factor c-Maf acts like an immune-system “programmer,” helping to decide when immune cells ramp up inflammation versus applying the brakes. However, rather than acting as simply an on/off switch, c-Maf functions more like a dimmer, shaping how immune cells develop and how much inflammation they produce. This new review explains how c-Maf functions as an immune checkpoint, shaping the development and behavior of many immune cell types, including T cells, B cells, innate lymphoid cells, and macrophages, and why that matters for autoimmune disease.
  • Autoimmune Diseases
  • IBD (Crohn’s and UC)
  • Lupus
  • Multiple Sclerosis
  • Research Studies
  • Therapies
  • Type 1 Diabetes
Read Post
Nov 24, 2025 NIH Clinical Trial Cuts Widen Gaps in Autoimmune Research
A new Research Letter published in JAMA Internal Medicine reports that 383 NIH-funded clinical trials lost grant support in the first half of 2025, disrupting studies involving more than 74,000 participants. Although the authors do not specify autoimmune-related trials, several disproportionately affected categories (such as prevention of disease onset trials, behavioral intervention type trials, and […]
  • Autoimmune Diseases
  • Clinical Trials
  • Policy & Health Decisions
  • Risk Factors
  • Therapies
Read Post