Eosinophilic fasciitis

Inflammation of the fascia (the tough band of tissue under the skin) along the arms and legs due to abnormal accumulation of white blood cells which causes skin swelling, thickening, and hardening. The symptoms typically impact both sides of the body but have also been seen to only impact one side.

Pain, swelling, inflammation of the skin (particularly on the arms and legs), venous grooving, reddening of the skin, limited mobility of affected areas, thickening/hardening of the skin, joints stuck in unnatural positions, localized areas of scleroderma, fatigue, weight loss, fever, malaise, weakness, muscle pain, joint pain, and bone pain.

Carpal tunnel syndrome, anemia, thrombocytopenia, and lymphoma.

According to some reports, females have a higher incidence than males. Those between roughly 30 and 60 years old are more commonly affected, but the disorder can occur at any age. Caucasians have been more greatly noted as having higher incidence. Being susceptible to allergic reactions is more commonly linked to eosinophilic fasciitis.

• Eosinophilic Fasciitis: Current and Remaining Challenges (2023)
• Eosinophilic fasciitis following SARS-CoV-2 vaccination (2023)
• Eosinophilic fasciitis (Shulman syndrome)-recognition of the histological spectrum allows for new insights into possible pathomechanisms (2023)
• Autoimmune comorbidities and antibody markers associated with eosinophilic fasciitis (2023)