A combination of endocrine and nonendocrine autoimmune diseases causing increased thyroid secretion and thyroid gland enlargement.
The three types of APS are:
- APS I: autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)
- Characterized by hypoparathyroidism, Addison’s disease, and chronic mucocutaneous candidiasis
- APS II: Schmidt Syndrome
- APS III: autoimmune polyglandular syndrome type 3