Autoimmune hyperlipidemia

Overview

Characterized by major hypertriglyceridemia, an abnormally high level of fat in the blood, due to autoantibodies preventing a specific type of protein (chylomicrons) in the plasma from properly circulating and transporting dietary lipids throughout the body.

Common Symptoms

At this time, more research is necessary. It remains unclear how much overlap there is between the autoimmune and genetic forms of the condition, the latter of which has been linked to symptoms of heart issues.

Coexisting Diseases and Conditions

Idiopathic thrombocytopenic purpura and Graves’ disease.

Risk Factors and Prevalence

Researchers have yet to discover risk factors for autoimmune hyperlipidemia. This is a field of study that needs more investigation.

Sources

  1. Article Sources and Footnotes

    1. American Journal of Managed Care. (n.d.). Epidemiology and Management of Hyperlipidemia. AJMC. https://www.ajmc.com/view/epidemiology-and-management-of-hyperlipidemia-article

    2. Baptist Health. (n.d.). Hyperlipidemia Signs, Symptoms & Treatment: Baptist Health. Baptist Health. https://www.baptisthealth.com/services/heart-care/conditions/hyperlipidemia. 

    3. Pruneta, V., Moulin, P., Labrousse, F., Bondon, P.-J., Ponsin, G., & Berthezene, F. (1997, March 1). Characterization of a New Case of Autoimmune Type I Hyperlipidemia: Long-Term Remission under Immunosuppressive Therapy1. OUP Academic. https://academic.oup.com/jcem/article/82/3/791/2656302