Dermatitis herpetiformis (DH)

 

 

Overview

Chronic skin rashes of bumps and blisters. The cause remains unknown, but genetics, gluten sensitivity, and other autoimmune diseases are believed to play a role. Some suspect that this is caused by deposits of immunoglobulin A (IgA) in the skin, which triggers additional immunologic reactions that form lesions. Typically DH is regarded as a manifestation of celiac disease, but less than 20% will have any of the other symptoms of celiac disease.

Common Symptoms

Off-and-on skin rashes, blisters, skin darkening or bumps, itching, and redness may be apparent, particularly along the elbows, knees, buttocks, and scalp. Tooth enamel can also develop horizontal grooves or discoloration in patients that also have celiac disease.

Coexisting Diseases and Conditions

Celiac disease, linear IgA disease, pemphigoid, eczema, hyperthyroidism, and scabies.

Sources

  1. Article Sources and Footnotes
    1. Dermatitis Herpetiformis. (n.d.). NORD (National Organization for Rare Disorders). Retrieved July 12, 2021, from https://rarediseases.org/rare-diseases/dermatitis-herpetiformis/

    2. Dermatitis Herpetiformis | NIDDK. (n.d.). National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved July 12, 2021, from https://www.niddk.nih.gov/health-information/professionals/clinical-tools-patient-management/digestive-diseases/dermatitis-herpetiformis

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