Treatments

Rheumatoid Arthritis Drug May Prevent Lung Damage From COVID

A recent study has indicated that the autoimmune disease drug anakinra aided in the prevention of lung damage and death in mice infected with SARS-CoV-2. Inflammatory lung vascular leakage can be presented in cases of severe COVID-19, when severe inflammation leads to the buildup of fluid in the lungs, and directly impacts the absorption of oxygen.

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Merck Submits COVID Antiviral Pill for EUA

This morning, the pharmaceutical company Merck submitted an application for EUA of their COVID-19 oral antiviral pill. If accepted, this will become the first pill authorized by the FDA to treat COVID-19. Other FDA authorized COVID-19 treatments must be administered intravenously or via injection.

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AstraZeneca Submits EUA for COVID Antibody Prophylaxis

AstraZeneca released a press release today stating that their long-acting antibody (LAAB) combination, AZD7442, has been shown to reduce the risk of symptomatic Covid-19 by 77% in a clinical trial. The trial included many participants who had medical conditions placing them at greater risk of severe illness and those who had not been producing sufficient antibodies after vaccination.

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WHO Endorses Regeneron’s COVID-19 Antibody Treatment

Last Friday, the WHO endorsed the use of Regeneron’s monoclonal antibody cocktail for patients at high risk of being hospitalized due to severe COVID-19. Others eligible for treatment include those unable to develop antibodies to COVID-19, through previous infection or vaccination. This includes immunocompromised persons. Regeneron’s casirivimab and imdevimab antibody cocktail, administered by infusion, was the first combination therapy to receive FDA EUA.

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