Research Studies

COVID-19 Versus Seasonal Influenza Outcomes in Autoimmune Disease Patients 

A recent multi-national study evaluated 30-day outcomes in hospitalized COVID-19 patients living with autoimmune disease (AD). Data was aggregated from centers including Columbia University Irving Medical Center and Information System for Research in Primary Care-Hospitalisation Linked Data in Spain. 133,589 patients diagnosed and 48,428 hospitalized with COVID-19 and living with autoimmune disease were included in the study.  

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Autoimmune Diseases Reported to be Triggered by SARS-CoV-2

The group at the Zabludowicz Center for Autoimmune Diseases of the Sheba Medical Center and the Laboratory of the Mosaic of Autoimmunity at Saint Petersburg State University have comprehensively investigated and reported the association between various common pathogenic viruses and the development of autoimmune and chronic inflammatory diseases. In light of the current global pandemic, they have also shifted their focus to include a recent (December 2020) review of the appearance of autoimmune diseases reported to be triggered by a SARS-CoV-2 infection.

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The VAXICOV Study, Autoimmune Disease and Vaccination Concerns

The results of the international VAccinations against COVid-19 (VAXICOV) study were published this week, revealing patient concerns and expectations around receiving the COVID-19 vaccine. Patients with systemic autoimmune or inflammatory rheumatic diseases were asked to participate in the online survey across 56 countries. Health care workers were also included as a control group. The most commonly documented autoimmune conditions were systemic lupus erythematosus, spondyloarthritis, and rheumatoid arthritis. The median score for patients who reported “being afraid to get infected” with COVID-19 was 8, and afraid to “develop severe COVID-19” was 9. That being said, only 54.2% of patients with systemic autoimmune or rheumatic disease were willing to get vaccinated against COVID-19 prior to seeing their specialist. 32.2% of patients were uncertain and 13% stated they were unwilling.

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