Type 1 Diabetes

Type 1 Diabetes occurs when the body’s immune system attacks insulin-producing pancreatic beta cells, causing the body to have insufficient insulin stores. Below are COVID news and research updates that specifically relate to Type 1 Diabetes.

How COVID-19 Triggers an Autoimmune Reaction

Researchers have hypothesized how a Covid-19 infection may trigger the development of autoimmune diseases through three different mechanisms, which may intersect at different points of the inflammatory process. Various autoimmune diseases include rheumatoid arthritis, ankylosing spondylitis, Guillain-Barre syndrome, as well as Hashimoto’s and Graves disease.

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Risk of Developing Autoimmune Disease Following COVID-19 Infection

A recent study exploring the association between COVID-19 infection and the risk of developing autoimmune diseases was conducted by a team of researchers from various institutions in Taiwan using data from the “TriNetX database, which holds the largest global COVID-19 dataset.” The team analyzed the medical record data of 3.8 million patients in the U.S., of which 888,460 had received a COVID-19 diagnosis (polymerase chain reaction–confirmed) between January 1, 2020, and December 31, 2021.

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COVID-19 in Patients with Systemic Autoimmune Rheumatic Diseases

Researchers evaluated the characteristics, severity, course of infection, and disease outcomes in COVID-19 patients with and without Systemic Autoimmune Rheumatic Diseases (SARDs). Patients with rheumatoid arthritis, systemic lupus erythematosus (SLE), Sjögren’s syndrome, Psoriasis, Type 1 Diabetes, Inflammatory Bowel Disease, and Glomerulonephritis, amongst others, were included in the study. 

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