SLE ( Systemic Lupus Erythematosus )

Systemic Lupus Erythematosus ( SLE ) is the most common form of lupus. Widespread inflammation and tissue damage of joints, skin, brain, lungs, kidneys, and blood vessels occur due to the immune system attacking its own healthy tissues. Below are COVID news and research updates that specifically relate to SLE.

Autoantibody Responses in Males versus Females Following COVID-19 Infection

Researchers at Cedars-Sinai recruited 177 healthcare workers with confirmed SARS-CoV-2 infection to study autoantibody levels depending on the severity of COVID-19 between males and females. 65% of the patients included in the study were female; 35% were male. Autoantibody reactivity was compared to a cohort of SLE patients, as well as 91 antigens which span typical autoimmune diseases.

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Covid-19 Outcomes in Autoimmune Disease Patients

Autoimmune disease is currently considered a risk factor for severe COVID-19. A research article published in Rheumatology last Fall summarized 30-day outcomes of autoimmune disease (AD) patients following hospitalization with COVID-19. AD patients diagnosed and/or hospitalized between January and June 2020 with COVID-19 were included, and their 30 day outcomes were compared to patients with at least one AD hospitalized with influenza from September 2017 through April 2018.

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