SLE ( Systemic Lupus Erythematosus )

Systemic Lupus Erythematosus ( SLE ) is the most common form of lupus. Widespread inflammation and tissue damage of joints, skin, brain, lungs, kidneys, and blood vessels occur due to the immune system attacking its own healthy tissues. Below are COVID news and research updates that specifically relate to SLE.

SLE Flares Post COVID-19 Vaccine

A study in Japan analyzed the association between mRNA Covid-19 vaccination and medium-term SLE flare-ups. At 30 days after completion of a primary series, the rate of mild or moderate SLE flares was 20.3% within the vaccinated group, versus 23.3% in the unvaccinated group. Flare rates at 60 and 90 days were similar between both groups. 

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IgG Antibody Responses Across 3 Doses of mRNA Vaccines

A study published in the Journal of Autoimmunity evaluated the immune response of Pfizer and Moderna’s mRNA COVID-19 vaccines in participants with autoimmune systemic diseases. In total, serum samples from 244 AD patients were collected 2-4 weeks and six months after their first vaccine cycle, and 2-4 weeks following their booster dose; 502 people from the general population were used as a control group.

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