Sjögren’s Syndrome

Sjögren's Syndrome occurs when the glands responsible for producing moisture in the eyes, mouth, and other parts of the body are destroyed by autoantibodies. Below are COVID news and research updates that specifically relate to Sjögren's.

Risk of Developing Autoimmune Disease Following COVID-19 Infection

A recent study exploring the association between COVID-19 infection and the risk of developing autoimmune diseases was conducted by a team of researchers from various institutions in Taiwan using data from the “TriNetX database, which holds the largest global COVID-19 dataset.” The team analyzed the medical record data of 3.8 million patients in the U.S., of which 888,460 had received a COVID-19 diagnosis (polymerase chain reaction–confirmed) between January 1, 2020, and December 31, 2021.

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COVID-19 in Patients with Systemic Autoimmune Rheumatic Diseases

Researchers evaluated the characteristics, severity, course of infection, and disease outcomes in COVID-19 patients with and without Systemic Autoimmune Rheumatic Diseases (SARDs). Patients with rheumatoid arthritis, systemic lupus erythematosus (SLE), Sjögren’s syndrome, Psoriasis, Type 1 Diabetes, Inflammatory Bowel Disease, and Glomerulonephritis, amongst others, were included in the study. 

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COVID-19 Vaccine Tolerance in Patients with Rheumatoid Arthritis

Researchers created an online questionnaire for RA and AIRD patients to self-report short-term COVID-19 vaccine-related adverse events. Vaccines included in the study were Pfizer, Moderna, Johnson & Johnson, AstraZeneca, Covaxin, and Sinopharm. The most common coexisting autoimmune diseases were thyroid disorders, systemic lupus erythematosus (SLE) and Sjogren’s syndrome (10.0%, 2.6%, and 2.5%, respectively).

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Long COVID & Systemic Autoimmune Rheumatic Diseases

Those suffering from systemic autoimmune rheumatic diseases have an increased risk of severe outcomes from a COVID-19 infection. Due to factors such as altered immunity or the use of immunosuppressive medications, they may also be at risk of developing Long COVID.

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