Autoantibodies & Long Covid

Researchers have identified several biomarkers correlating with long Covid symptoms, further suggesting an autoimmune process activating one year post-Covid infection.

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COVID-19 Severity and Autoantibody Production

To better characterize the immunopathology of COVID-19, researchers studied the range of autoantibodies triggered by a SARS-CoV-2 infection, as well as infection severity. Generally, the autoantibodies in patients with mild COVID-19 only slightly differed compared to healthy controls. Patients with moderate COVID-19 exhibited more elevated autoantibody counts, whereas those with severe COVID-19 were observed to have the highest levels of autoantibodies.

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COVID-19 Drives Autoimmunity

This Week in Virology podcast discusses the finding that infection with SARS-CoV-2 leads to an increase in new and preexisting autoantibodies. Find the episode here!

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