Goodpasture’s syndrome/Anti-GBM/anti-TBM disease

 

Overview

Autoantibodies attack the lungs and kidneys and if left untreated this can quickly escalate to glomerulonephritis, kidney failure, or even death.

Common Symptoms

Bleeding in the lungs, fatigue, nausea, breathing issues, vomiting, pale skin, burning sensations when urinating, blood in the urine, protein in the urine, coughing, foamy urine, swelling of the legs, and high blood pressure.

Coexisting Diseases and Conditions

Hemoptysis, dyspnea, hypertension, arthritis, anemia, acute kidney failure, chronic kidney disease, heart disease, and respiratory failure.

Risk Factors and Prevalence

Male sex, age between 20 and 30, or over 60, having certain genes, and environmental triggers such as exposure to chemicals or metallic dust, viral infections, smoking, hair dyes, hydrocarbon fumes, or certain medications.

Sources

  1. Article Sources and Footnotes

    1. Goodpasture Syndrome. (n.d.-a). NORD (National Organization for Rare Disorders). Retrieved June 12, 2021, from https://rarediseases.org/rare-diseases/goodpasture-syndrome/

    2. Goodpasture Syndrome. (n.d.-b). Retrieved June 12, 2021, from https://www.hopkinsmedicine.org/health/conditions-and-diseases/goodpasture-syndrome

    3. Goodpasture Syndrome (Anti-GBM Disease): What It is & Diagnosis. (n.d.). Cleveland Clinic. Retrieved July 12, 2021, from https://my.clevelandclinic.org/health/diseases/5927-goodpasture-syndrome