Autoimmune Disease List

There are over 90 known autoimmune diseases and counting, affecting at least 23.5 million Americans – though research indicates that numbers have been growing steadily for years. Many more conditions are autoimmune-related, or include suspected autoimmune components. With regard to some conditions, there can be differing opinions and conflicting research on various aspects and their relationships with autoimmunity.

This is an evolving list since many autoimmune diseases overlap, co-exist, and share symptoms; some of the diseases listed here are variants or subtypes of other diseases. Our understanding of these conditions is constantly shifting as more information comes to light. 

The collection below is meant to serve as a helpful guide, and a starting point for your own research as a person with diagnosed or undiagnosed conditions – whether you’re unsure if you have an autoimmune disease or you think you may have more than one (having three or more is known as Multiple Autoimmune Syndrome or MAS).

Also noted on this list are rare autoimmune conditions, which have been collected from the National Organization of Rare Disorders (NORD) Rare Disease Database. NORD states that “in the United States, any disease affecting fewer than 200,000 people is considered rare.”

KEY:
*autoimmune-related or suspected autoimmune disorder
rare disorder +
also known by another name on this list

A

Acute disseminated encephalomyelitis (ADEM) +

Acute hemorrhagic leukoencephalitis (AHLE) / Hurst’s disease +

Agammaglobulinemia, primary +

Alopecia areata +

Ankylosing spondylitis

Anti-GBM/anti-TBM disease / Goodpasture’s syndrome

Antiphospholipid antibody syndrome (APS) +

*Arteriosclerosis

*Autism spectrum disorders (ASD)

Autoimmune Addison’s disease +

Autoimmune aplastic anemia +

Autoimmune dysautonomia

Autoimmune hemolytic anemia +

Autoimmune hepatitis +

Autoimmune hyperlipidemia

Autoimmune inner ear disease (AIED)

Autoimmune interstitial cystitis

Autoimmune lymphoproliferative syndrome (ALPS)

Autoimmune myocarditis

Autoimmune polyendocrine syndrome / Schmidt syndrome +

Autoimmune polyglandular syndromes, Types I, II, & III +

Autoimmune progesterone dermatitis

Autoimmune thrombocytopenic purpura (ATP) / immune thrombocytopenic purpura (ITP) +

Autoimmune thyroiditis

B

Balo disease +

Behçet’s disease +

Bullous pemphigoid +

C

*Castleman disease +

Celiac disease

*Chagas disease

*Chronic fatigue syndrome / myalgic encephalomyelitis

Chronic inflammatory demyelinating polyneuropathy (CIDP) +

Churg-Strauss syndrome +

Cicatricial pemphigoid +

Cogan’s syndrome +

Cold agglutinin disease +

CREST syndrome

Crohn’s disease

*Cronkhite-Canada syndrome (CSS) +

D

Dermatomyositis +

Devic’s disease / neuromyelitis optica +

Diabetes, type 1

Discoid lupus

*Dressler’s syndrome / postmyocardial infarction / postpericardiotomy syndrome

E

*Endometriosis

Eosinophilic fasciitis +

*Erythema nodosum

*Essential mixed cryoglobulinemia +

Evans syndrome +

F

*Fibrosing alveolitis

G

*Giant cell arteritis / temporal arteritis / Horton’s disease +

Glomerulonephritis

Goodpasture’s syndrome / Anti-GBM/anti-TBM disease

Grave’s disease +

Guillain-Barré syndrome +

H

Hashimoto’s thyroiditis

Henoch-Schönlein purpura +

Herpes gestationis / pemphigoid gestationis +

*Horton’s disease / temporal arteritis / giant cell arteritis +

Hurst’s disease / acute hemorrhagic leukoencephalitis

*Hypogammaglobulinemia

I

IgA nephropathy +

Immune thrombocytopenic purpura (ITP) / autoimmune thrombocytopenic purpura (ATP)

J

Juvenile arthritis

K

*Kawasaki syndrome +

L

Lambert-Eaton myasthenic syndrome (LEMS) +

*Leukocytoclastic vasculitis

Lichen planus +

*Lichen sclerosus +

*Ligneous conjunctivitis +

Linear IgA disease (LAD)

Lupus nephritis

*Lyme disease

M

Ménière’s disease

Microscopic polyangiitis

Mixed connective tissue disease (MCTD) +

*Mooren’s ulcer

*Mucha-Habermann disease +

Multiple sclerosis

*Myalgic encephalomyelitis / chronic fatigue syndrome

Myasthenia gravis +

N

Neuromyelitis optica / Devic’s disease +

*Narcolepsy +

Non-length-dependent small fiber sensory neuropathy

O

Ocular cicatricial pemphigoid +

P

Palindromic rheumatism

Palmoplantar pustulosis (type of psoriasis)  +

Paraneoplastic cerebellar degeneration +

Paroxysmal nocturnal hemoglobinuria (PNH) +

*Pars planitis / peripheral uveitis +

*Peripheral uveitis / pars planitis +

Parsonage Turner syndrome +

Pemphigoid gestationis / herpes gestationis

Pemphigus vulgaris +

Pernicious anemia +

POEMS syndrome +

Polyarteritis nodosa +

Polymyalgia rheumatica +

Polymyositis +

*Postmyocardial infarction / postpericardiotomy syndrome / Dressler’s syndrome

*Postpericardiotomy syndrome / postmyocardial infarction / Dressler’s syndrome

Primary biliary cirrhosis

*Progesterone dermatitis

Psoriasis

Psoriatic arthritis +

Pulmonary fibrosis, idiopathic (IPF) +

Pure red cell aplasia +

*Pyoderma gangrenosum +

R

Raynaud’s disease

*Reflex sympathetic dystrophy

Reiter’s syndrome

Relapsing polychondritis +

*Restless leg syndrome / Willis-Ekbom disease +

Rheumatic fever

Rheumatoid arthritis

S

Sarcoidosis

Schmidt syndrome / autoimmune polyendocrine syndrome

Scleritis

Scleroderma +

Sjögren’s syndrome

*Stiff person syndrome (SPS) +

Systemic lupus erythematosus (SLE)

*Subacute bacterial endocarditis (SBE)

*Sympathetic ophthalmia

T

*Takayasu’s arteritis

*Temporal arteritis / Horton’s disease / giant cell arteritis

Testicular autoimmunity

*Tolosa-Hunt syndrome +

Transverse myelitis (TM) +

U

Ulcerative colitis +

Undifferentiated connective tissue disease (UCTD)

*Uveitis, anterior

*Uveitis, intermediate

*Uveitis, posterior +

V

Vasculitis

Vitiligo

W

Wegener’s granulomatosis

*Willis-Ekbom disease / restless leg syndrome +

 

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