Presented at the 13th International Congress on Autoimmunity in Athens, Greece
Speaker: Aaron Lerner
Speaker: Aaron Lerner
The guidelines for the diagnosis of celiac disease (CD) recommend using CD serology for the screening and diagnosing of CD.
The current standard of classical serological markers for the diagnosis of CD has its limitations. Therefore, a new generation of markers should be considered and developed.
83% of Americans who have CD are undiagnosed or misdiagnosed with other conditions. Late diagnosis has long-term complications: short stature, osteoporosis, enamel defects, nutritional deficiencies, cancer predisposition, and susceptibility to other autoimmune diseases. Lerner proposed that the tTG neo-epitope should be considered as a new diagnostic marker for CD.
The tTG neo-epitope has:
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